Does Plexus VitalBiome work?

The dynamics of the new age and the many obligations can sometimes affect our mental health and the health of the digestive system. It is due to the irregular diet and fast food that we consume daily.

Recent research1 has shown that the health of the digestive system is closely related to mental health.

Besides, the gut is where 90% of the body’s serotonin is produced and is home to 70% of immune cells. Therefore, if the intestinal microflora is disturbed, the consequences for your health can be multifaceted. 

To restore balance, here you have a natural alternative. So keep reading to see all the advantages provided by Plexus VitalBiome.

What Exactly Is Plexus VitalBiome?

VitalBiome is a probiotic that is composed of eight components that your gut needs. 

Plexus made sure to make an effective combination of several probiotic strains that have been clinically proven to work. Such strains can help balance all the metabolic processes in your gut.

Namely, this product contains 7 billion CFU (colony-forming units). Such colonies of eight probiotic strains enrich the intestinal microflora and help fight infections and inflammation.

What is Plexus VitalBiome used for?

As mentioned previously, VitalBiome is a formula that aims to restore the balance of the gut. In addition, this product may help reduce anxiety, stress, and stomach pains and help against inflammatory issues.

The Science and Ingredients Behind VitalBiome

This product is designed to primarily act on the gut microbiome. With this action, VitalBiome replenishes the lost microbes that are important for the intestinal microflora.

Probiotics are known to play a significant role in the health of the intestinal microflora. In addition, taking probiotics has been shown to be effective for the immune system2, weight loss3 and bacterial balance in the gut.4

And not only that, it has been shown that probiotics play a role in improving digestion5 as well as in the fight against gastrointestinal diseases. 6

That’s why here you can find a detailed explanation to see the benefits and effectiveness of VitalBiome’s probiotic strains. In addition, you’ll get to know more about the in-depth research and clinical trials associated with these strains. 

Lactobacillus helveticus

Lactobacillus helveticus is a bacterium that produces lactic acid. In addition to intestinal microflora, it is also found in foods such as Swiss cheese, parmesan, mozzarella, fermented foods, kefir, and the like. This bacterium is important because it works to improve oral, intestinal, and mental health in humans.

This is evidenced by numerous studies where this bacterium has been shown to be good for gut health7, preventing periodontitis8, regulating blood pressure9, and improving mental health.10

Bacillus coagulans

Bacillus coagulans is a bacterium found in the intestinal flora. Unlike Lactobacillus helvetica, it can generate spores and is quite resistant to extreme conditions. Therefore, this bacterium can be effective against stomach upsets and other types of ailments. 

Although a small number of trials have been conducted, this bacterium has been shown to be effective in treating irritable bowel syndrome (IBS)11 , Rheumatoid arthritis 12, and postoperatively in gynecological laparoscopic surgery.13

Bifidobacterium lactis

Bifidobacterium lactis is one of the most well-known and studied bacteria found in the gut. Including this bacterium in the VitalBiome formula only improves gut function and can help defend against infections. 

From the numerous studies found, it’s noticed that this bacteria helps improve oral health 14, the gastrointestinal system 15, blood sugar 16, and more.

Bifidobacterium longum

This bacterium is another in a series of probiotic strains that positively affect gut health. Namely, bifidobacteria can help deal with diarrhea and constipation and help improve general health. According to research on this bacterium, it has been shown to successfully assist in dealing with irritable bowel syndrome.17

Saccharomyces Boulardii

Saccharomyces Boulardii is a yeast that has been shown to be quite effective in supporting gut health. Namely, studies have shown that Saccharomyces Boulardii can help with various conditions, such as disorders associated with intestinal barrier disruption18, regeneration of the intestinal microbiota19, and intestinal infections.20

Bifidobacterium lactis bi-07

According to some clinical trials, this bacterium may aid lactose digestion.21 In addition, it can stimulate phagocytosis in monocytes and granulocytes.22

Lactobacillus plantarum

Lactobacillus plantarum is used in diseases related to the intestine, inflammatory processes, diarrhea, constipation, and respiratory infections. Although numerous studies23are positive, additional studies are needed to prove the effectiveness of this bacteria.

Lactobacillus acidophilus NCFM

This bacteria, like the others, helps the health of the gut. In addition, it can help with conditions such as diarrhea and bloating. In clinical research, it has been shown to be effective against abdominal bloating.24

Plexus VitalBiome vs. Other Supplements

Choosing the right probiotic can sometimes be very difficult. Especially when there are many products with different prices in the supplement market. For that purpose, only a few supplements were compared in their price, effectiveness, and composition with VitalBiome.

Buy Plexus VitalBiome Directly

When comparing the price of VitalBiome to other products, the price is a lot higher. If you want to purchase this product at a premium, fill out this form, and a good and honest Plexus ambassador will contact you. Alternatively, you can get VitalBiome through other websites like Amazon. Ordering is quick and simple.

Better Value Alternatives

Regarding the effect of VitalBiome and its composition, you’ll notice that there are many similar products with different probiotic strains at a much better value.

Puritan’s Pride – Probiotic 10 – the positive thing about this probiotic is that it is a combination of probiotic strains combined with vitamin D. On the other hand, it contains bacteria from only two families: Lactobacillus and Bifidobacterium.

NOW Supplements – Saccharomyces boulardii – is a probiotic used to improve intestinal microflora. The good thing about this probiotic is that it contains only one strain, Saccharomyces boulardii. That way, if you want to get the benefits of this strain, it is worth the price. On the other hand, VitalBiome is a blend of multiple strains that have the same goal, improving gut health.

Garden of Life – Primal Defense Ultra is a probiotic combination of several probiotic strains. The manufacturer claims it can help improve the immune system and gut health. When considering the composition, it’s noticeable that it contains several families of bacteria that have been proven with their actions. The only downside is the price which is higher compared to VitalBiome.

$30.79Puritan’s Pride – Probiotic 10$0.17/dose
$21.99NOW Supplements – Saccharomyces boulardii$0.37/dose
$37.99Garden of Life – Primal Defense Ultra$0.42/dose
Plexus VitalBiome$2/dose

When to Take Plexus VitalBiome

This product is best taken on an empty stomach. In addition, you can also take it after a meal. Probiotics are safe to use, especially if you are faced with irregular and unhealthy food, reduced physical activity as well as stress, and anxiety.

In addition, this product is intended for people over 18 years of age. Just one capsule a day is enough to restore the balance of your intestinal microflora.

Is Plexus VitalBiome Safe to Use?

Yes, just like other probiotics, VitalBiome is safe to use. It is confirmed by many clinical trials that testify to the positive characteristics of probiotic strains. However, before you start taking this product, it is best to consult your doctor. Keep in mind that this product must not replace regular therapy or medications prescribed by a doctor.

Who Can Use Plexus VitalBiome

This product can be used by any adult who wants to enrich the gut microbiome. Although VitalBiome is generally safe to use, a special group of people should be careful before taking it.

Pregnant and nursing women, people with chronic diseases, those taking regular therapy, and people with allergies are best to consult a doctor before purchasing this product.

Frequently Asked Questions

Does Plexus VitalBiome help with stress?

The manufacturer of VitalBiome has stated that this product may help deal with anxiety, stress, and nervousness. However, please note that this product is not intended to treat or cure disease. Therefore, consult a doctor before purchasing it.

Is VitalBiome gluten-free, vegetarian, and non-GMO?

Yes. According to their official website, this product, besides not containing GMOs, does not contain any artificial additives. That way, you don’t need to worry about getting side effects.

What are the ingredients of VitalBiome?

In addition to the main ingredients that are mentioned above in the text, you can find the rest of the ingredients on their official website, which include brown rice flour, hypromellose, medium-chain triglycerides, milk, and soy. Check them carefully if you have an allergic reaction to similar products.


When it comes to general health, gut health should not be neglected. Having countless daily responsibilities, fast food, and an irregular diet can cause a big problem related to digestion and the functionality of the digestive system. 

The use of probiotics has been shown to be effective in the fight against unhealthy diets and weak health. However, remember that probiotics like VitalBiome aren’t magic pills that will solve all your problems. It is best to pay attention to your diet, regular physical activity, and preventive measures related to your health.

At the very end, VitalBiome is a nutritional supplement. In that regard, it mustn’t, in any case, replace the regular meal or be a substitute for medicines prescribed by a doctor. If you are facing a severe health problem, it is best to consult your doctor.


  1. Clapp M, Aurora N, Herrera L, Bhatia M, Wilen E, Wakefield S. Gut microbiota’s effect on mental health: The gut-brain axis. Clin Pract. 2017 Sep 15;7(4):987. doi: 10.4081/cp.2017.987. PMID: 29071061; PMCID: PMC5641835.
  2. González de Llano D, Moreno-Arribas MV, Bartolomé B. Cranberry Polyphenols and Prevention against Urinary Tract Infections: Relevant Considerations. Molecules. 2020 Aug 1;25(15):3523. doi: 10.3390/molecules25153523. PMID: 32752183; PMCID: PMC7436188
  3. Álvarez-Arraño V, Martín-Peláez S. Effects of Probiotics and Synbiotics on Weight Loss in Subjects with Overweight or Obesity: A Systematic Review. Nutrients. 2021 Oct 17;13(10):3627. doi: 10.3390/nu13103627. PMID: 34684633; PMCID: PMC8540110.
  4. Tang C, Lu Z. Health promoting activities of probiotics. J Food Biochem. 2019 Aug;43(8):e12944. doi: 10.1111/jfbc.12944. Epub 2019 Jun 14. PMID: 31368544.
  5. Markowiak P, Śliżewska K. Effects of Probiotics, Prebiotics, and Synbiotics on Human Health. Nutrients. 2017 Sep 15;9(9):1021. doi: 10.3390/nu9091021. PMID: 28914794; PMCID: PMC5622781.
  6. Guo Q, Goldenberg JZ, Humphrey C, El Dib R, Johnston BC. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2019 Apr 30;4(4):CD004827. doi: 10.1002/14651858.CD004827.pub5. PMID: 31039287; PMCID: PMC6490796.
  7. Health-Promoting Properties of Lactobacillus helveticus
  8. Lactobacillus helveticus Prevents Periodontitis Induced by Aggregatibacter actinomycetemcomitans in Rats by Regulating β-Defensins
  9. Effect of powdered fermented milk with Lactobacillus helveticus on subjects with high-normal blood pressure or mild hypertension
  10. Beneficial psychological effects of a probiotic
    formulation (Lactobacillus helveticus R0052 and
    Bifidobacterium longum R0175) in healthy human
  11. The efficacy of a synbiotic containing Bacillus Coagulans in treatment of irritable bowel syndrome: a randomized placebo-controlled trial
  12. Bacillus coagulans: a viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial
  13. Bacillus coagulans TBC169 probiotics for the recovery of intestinal function after gynecological laparoscopic surgery: a randomized, placebo-controlled trial
  14. Impact of orally administered lozenges with Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12 on the number of salivary mutans streptococci, amount of plaque, gingival inflammation and the oral microbiome in healthy adults
  16. Potential probiotic Bifidobacterium animalis ssp. lactis 420 prevents weight gain and glucose intolerance in diet-induced obese mice
  17. Bifidobacterium Longum: Protection against Inflammatory Bowel Disease
  18. Beneficial effects of Saccharomyces boulardii CNCM I-745 on clinical disorders associated with intestinal barrier disruption
  19. Saccharomyces boulardii CNCM I-745 supports regeneration of the intestinal microbiota after diarrheic dysbiosis – a review
  20. Diversity of Saccharomyces boulardii CNCM I-745 mechanisms of action against intestinal infections
  21. Impact of orally administered lozenges with Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12 on the number of salivary mutans streptococci, amount of plaque, gingival inflammation and the oral microbiome in healthy adults
  22. Consumption of Bifidobacterium lactis Bi-07 by healthy elderly adults enhances phagocytic activity of monocytes and granulocytes
  23. Lactobacillus plantarum
  24. Clinical trial: Probiotic Bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 Versus Placebo for the Symptoms of Bloating in Patients with Functional Bowel Disorders – a Double-Blind Study
About the author

Hans Mast is someone who has always loved science and been passionate about truth. Overhyped claims drive him nuts. He loves to strip away the emotionally-charged sales pitches and hone in on the actual facts. HVG is his attempt to provide that as a service to the world of vitamins, supplements, and herbs.

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